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Peptide record

TPDB04194

Antibacterial Antifungal standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB04194
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VVYTLKRNGRTLYGF
Physicochemical Analysis
C83H131N23O21
ADCEQHIMPSW
RGLTYV
1787.09
10.59
3
0
7
+3
-0.66
-0.160
90.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
2980
166.75
5
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
2
L
1
K
0
M
1
F
0
P
0
S
2
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 2 K: 1 M: 0 F: 1 P: 0 S: 0 T: 2 W: 0 Y: 2 V: 2
Chemical Descriptors
15
C83H131N23O21
1787.09
10.59
+3
-0.66
-0.160
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (LD90 10.3 ug/ml), P. aeruginosa LD90 8.7 ug/ml), and B. subtilis (LD90 14 ug/ml). ATP can enahnce its activity, implying its involvement in inhibiting the DNA gyrase activity.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (LD90 10.3 ug/ml), P. aeruginosa LD90 8.7 ug/ml), and B. subtilis (LD90 14 ug/ml). ATP can enahnce its activity, implying its involvement in inhibiting the DNA gyrase activity.