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Peptide record

TPDB04183

Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB04183
Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb CPPsite3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LLLFLLKKRKKRKY
Physicochemical Analysis
C90H159N25O16
ANDCEQGHIMPSTWV
LK
1847.41
11.70
7
0
7
+7
1.70
-0.571
139.29
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
80.65
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C90H159N25O16
1847.41
11.70
+7
1.70
-0.571
Evidence Records 5 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
58±23 µM
Hemolytic Cytotoxic
50% Hemolysis | 58±23 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
99±10 µM
Hemolytic Cytotoxic
50% Hemolysis | 99±10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
65±15 µM
Hemolytic Cytotoxic
50% Hemolysis | 65±15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
29±2.5 µM
Hemolytic Cytotoxic
50% Hemolysis | 29±2.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis