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Peptide record

TPDB04161

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB04161
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
YTLGIKILWSAYKH
Physicochemical Analysis
C83H125N19O19
RNDCEQMFPV
ILKY
1693.02
9.97
3
0
8
+2
-2.42
0.143
118.57
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
8480
500.88
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
2
L
2
K
0
M
0
F
0
P
1
S
1
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 2 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 2 V: 0
Chemical Descriptors
14
C83H125N19O19
1693.02
9.97
+2
-2.42
0.143
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Plantaricin NC8 alpha beta Exerts Potent Antimicrobial Activity Against Staphylococcus Spp. And Enhances the Effects of Antibiotics. | Sci Rep | 2020