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Peptide record

TPDB04145

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB04145
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSAITSLLGKLL
Physicochemical Analysis
C66H114N14O17
RNDCEQHMPWYV
L
1375.71
10.10
1
0
8
+1
-3.01
1.654
187.69
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
5
L
1
K
0
M
1
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 5 K: 1 M: 0 F: 1 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C66H114N14O17
1375.71
10.10
+1
-3.01
1.654
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus (MIC 6 uM). Warning: other bacteria not tested. Updated 3/2012 GW.
Evidence 2 Activity

Activity

MIC
Antifungal
6 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus (MIC 6 uM). Warning: other bacteria not tested. Updated 3/2012 GW.
Evidence 3 Activity

Activity

MIC
Antiparasitic
6 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus (MIC 6 uM). Warning: other bacteria not tested. Updated 3/2012 GW.
Evidence 4 Activity

Activity

MIC
Antiviral
6 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus (MIC 6 uM). Warning: other bacteria not tested. Updated 3/2012 GW.
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
60 µM
Hemolytic Cytotoxic
50% Hemolysis | 60 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis). | Comp Biochem Physiol C Toxicol Pharmacol | 2004
Evidence 6 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.