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Peptide record

TPDB04133

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB04133
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
RLWDIVRRWVGWL
Physicochemical Analysis
C85H127N25O16
ANCEQHKMFPSTY
RW
1755.10
12.10
3
1
8
+2
-3.17
0.031
134.62
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
940.12
0
Residue Composition
number
0
A
3
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 2
Chemical Descriptors
13
C85H127N25O16
1755.10
12.10
+2
-3.17
0.031
Evidence Records 3 records
Evidence 1 Activity

Activity

15% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
15% Hemolysis | 50 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Aurein-derived antimicrobial peptides formulated with pegylated phospholipid micelles to target methicillin-resistant Staphylococcus aureus skin infections. | ACS Infect Dis | 2018
Evidence 2 Activity

Activity

30% Cytotoxicity
Toxicity
50 µg/mL
Cytotoxic
30% Cytotoxicity | 50 | µg/mL | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Aurein-derived antimicrobial peptides formulated with pegylated phospholipid micelles to target methicillin-resistant Staphylococcus aureus skin infections. | ACS Infect Dis | 2018
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis