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Peptide record

TPDB04125

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB04125
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LLPIVGNLLNSLL
Physicochemical Analysis
C65H115N15O17
ARDCEQHKMFTWY
L
1378.72
6.02
0
0
8
-0
-2.17
1.669
232.31
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
6
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 6 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C65H115N15O17
1378.72
6.02
-0
-2.17
1.669
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
It only showed weak activity against B. megaterium.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
It only showed weak activity against B. megaterium.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

It only showed weak activity against B. megaterium.
Evidence 4 Activity

Activity

% Hemolysis
Toxicity
55 %
Hemolytic
Hemolytic_activity: [Ref.10691983]55% hemolysis at 10 µM, 90% hemolysis at 20 µM, 95% hemolysis at 40µM, 100% hemolysis at 60 µM against human red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Biochem. 1996 Dec 15 242(3):788-792.##Eur J Biochem. 2000 Mar 267(5):1447-54.
Evidence 5 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.