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Peptide record

TPDB04094

Antibacterial standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB04094
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLLWHLLHHLLH
Physicochemical Analysis
C73H109N21O13
ARNDCEQIKMFPSTYV
L
1488.80
8.15
4
0
7
+0
-1.36
0.725
195.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
369.42
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
4
H
0
I
6
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 4 I: 0 L: 6 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C73H109N21O13
1488.80
8.15
+0
-1.36
0.725
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.7-32 µg/mL

Target

S. salivarius

Source & Reference

NA

Other

active against oral pathogens streptococci such as S. mutans, S. sobrinus and S. salivarius (MIC 6.7-32 ug/ml). Active against oral Cariogenic Bacteria: S. mutans UA159 (MIC 8 ug/ml), S. gordonii DL1
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. mutans UA159

Source & Reference

NA

Other

. sobrinus and S. salivarius (MIC 6.7-32 ug/ml). Active against oral Cariogenic Bacteria: S. mutans UA159 (MIC 8 ug/ml), S. gordonii DL1 (MIC 8 ug/ml), S. sanguinis ATCC10556 (MIC 8 ug/ml), L. acidophilus ATCC
Evidence 3 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. gordonii DL1

Source & Reference

NA

Other

IC 6.7-32 ug/ml). Active against oral Cariogenic Bacteria: S. mutans UA159 (MIC 8 ug/ml), S. gordonii DL1 (MIC 8 ug/ml), S. sanguinis ATCC10556 (MIC 8 ug/ml), L. acidophilus ATCC14931 (MIC 4 ug/ml), L. casei A
Evidence 4 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. sanguinis ATCC10556

Source & Reference

NA

Other

t oral Cariogenic Bacteria: S. mutans UA159 (MIC 8 ug/ml), S. gordonii DL1 (MIC 8 ug/ml), S. sanguinis ATCC10556 (MIC 8 ug/ml), L. acidophilus ATCC14931 (MIC 4 ug/ml), L. casei ATCC393 (MIC 4 ug/ml), L. fermentium AT
Evidence 5 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

L. acidophilus ATCC14931

Source & Reference

NA

Other

UA159 (MIC 8 ug/ml), S. gordonii DL1 (MIC 8 ug/ml), S. sanguinis ATCC10556 (MIC 8 ug/ml), L. acidophilus ATCC14931 (MIC 4 ug/ml), L. casei ATCC393 (MIC 4 ug/ml), L. fermentium ATCC9338 (MIC 4 ug/ml), A. viscosus ATCC15
Evidence 6 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

L. casei ATCC393

Source & Reference

NA

Other

C 8 ug/ml), S. sanguinis ATCC10556 (MIC 8 ug/ml), L. acidophilus ATCC14931 (MIC 4 ug/ml), L. casei ATCC393 (MIC 4 ug/ml), L. fermentium ATCC9338 (MIC 4 ug/ml), A. viscosus ATCC15987 (MIC 8 ug/ml), and A. naeslu
Evidence 7 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

L. fermentium ATCC9338

Source & Reference

NA

Other

56 (MIC 8 ug/ml), L. acidophilus ATCC14931 (MIC 4 ug/ml), L. casei ATCC393 (MIC 4 ug/ml), L. fermentium ATCC9338 (MIC 4 ug/ml), A. viscosus ATCC15987 (MIC 8 ug/ml), and A. naeslundii ATCC12104 (MIC 4 ug/ml). Warning:
Evidence 8 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

A. viscosus ATCC15987

Source & Reference

NA

Other

4931 (MIC 4 ug/ml), L. casei ATCC393 (MIC 4 ug/ml), L. fermentium ATCC9338 (MIC 4 ug/ml), A. viscosus ATCC15987 (MIC 8 ug/ml), and A. naeslundii ATCC12104 (MIC 4 ug/ml). Warning: other bacteria not tested (Gram-). I
Evidence 9 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

A. naeslundii ATCC12104

Source & Reference

NA

Other

4 ug/ml), L. fermentium ATCC9338 (MIC 4 ug/ml), A. viscosus ATCC15987 (MIC 8 ug/ml), and A. naeslundii ATCC12104 (MIC 4 ug/ml). Warning: other bacteria not tested (Gram-). Inhibited biofilm formation.