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Peptide record

TPDB04039

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB04039
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
PLLKKLLKKP
Physicochemical Analysis
C58H108N14O11
ARNDCEQGHIMFSTWYV
LK
1177.58
11.00
4
0
4
+4
2.62
-0.360
156.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C58H108N14O11
1177.58
11.00
+4
2.62
-0.360
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >500 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Designing α-helical peptides with enhanced synergism and selectivity against Mycobacterium smegmatis: Discerning the role of hydrophobicity and helicity. | Acta Biomater | 2015