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Peptide record

TPDB04006

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB04006
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
WWLWWLRWL
Physicochemical Analysis
C79H97N17O10
ANDCEQGHIKMFPSTYV
W
1444.75
11.05
1
0
8
+1
-10.12
0.267
130.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
27500
1903.45
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
9
C79H97N17O10
1444.75
11.05
+1
-10.12
0.267
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
57.5 µM
Cytotoxic
50% Cell death | 57.5 | µM | target cell: Human Primary Epidermal Keratinocytes (HEK)

Target

Human Primary Epidermal Keratinocytes (HEK)

Source & Reference

NA
DBAASP
Designing an ultra-short antibacterial peptide with potent activity against Mupirocin-resistant MRSA. | Chem Biol Drug Des | 2018