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Peptide record

TPDB03994

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB03994
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
CLLKKLLKK
Physicochemical Analysis
C51H99N13O10S1
ARNDEQGHIMFPSTWYV
LK
1086.49
10.55
4
0
4
+4
1.48
0.233
173.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C51H99N13O10S1
1086.49
10.55
+4
1.48
0.233
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>1000 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >1000 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Anti-mycobacterial activities of synthetic cationic α-helical peptides and their synergism with rifampicin. | Biomaterials | 2014