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Peptide record

TPDB03976

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB03976
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
HFRWGKPV
Physicochemical Analysis
C50H71N15O9
ANDCEQILMSTY
RGHKFPWV
1026.21
11.49
3
0
3
+2
0.31
-0.938
36.25
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
5500
535.95
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
0
L
1
K
0
M
1
F
1
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
8
C50H71N15O9
1026.21
11.49
+2
0.31
-0.938
Evidence Records 2 records
Evidence 1 Activity

Activity

<1% Hemolysis
Toxicity
<62.5 µM
Hemolytic Cytotoxic
<1% Hemolysis | <62.5 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Lipidated Short Analogue of α-Melanocyte Stimulating Hormone Exerts Bactericidal Activity against the Stationary Phase of Methicillin-Resistant Staphylococcus aureus and Inhibits Biofilm Formation. | ACS Omega | 2020
Evidence 2 Activity

Activity

0% Killing
Toxicity
50 µM
Cytotoxic
0% Killing | 50 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Lipidated Short Analogue of α-Melanocyte Stimulating Hormone Exerts Bactericidal Activity against the Stationary Phase of Methicillin-Resistant Staphylococcus aureus and Inhibits Biofilm Formation. | ACS Omega | 2020