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Peptide record

TPDB03949

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB03949
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept dbAMP 3.0 AI4AVP DRAMP DRAVP 2.0
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
GDPTFCGETCRVIPVCTYSAALGCTCDDRSDGLCKRN
Physicochemical Analysis
C159H256N48O56S6
QHMW
C
3928.43
4.56
4
5
9
-1
7.40
-0.189
52.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
47.47
14
Residue Composition
number
2
A
3
R
1
N
4
D
6
C
1
E
0
Q
4
G
0
H
1
I
2
L
1
K
0
M
1
F
2
P
2
S
4
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 4 C: 6 E: 1 Q: 0 G: 4 H: 0 I: 1 L: 2 K: 1 M: 0 F: 1 P: 2 S: 2 T: 4 W: 0 Y: 1 V: 2
Chemical Descriptors
37
C159H256N48O56S6
3928.43
4.56
-1
7.40
-0.189
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
1.5 µM
Cytotoxic
IC50 | 1.5 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

EC50
Toxicity
0.10 Μm
Cytotoxic
Cytotoxicity: [Ref.11430013] Cytotoxicity: human T-lymphoblastoid cell line (CEM-SS)(EC50=0.10 Μm, IC50=1.5 µM) . ##[Ref.18008336]CEM-SS cells:IC50=1500 nM.

Source & Reference

NA
DRAMP
J Nat Prod. 2001 Feb 64(2):249-250.##Structure. 2004 Jan 12(1):85-94.##Biopolymers. 2008 90(1):51-60.