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Peptide record

TPDB03941

GMA4C Antibacterial Antifungal Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB03941
GMA4C
Antibacterial Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP CPPsite3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Antifungal, and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GRCRGFRRRCFCTTHC
Physicochemical Analysis
C78H127N33O19S4
ANDEQILKMPSWYV
R
1959.32
10.72
6
0
2
+5
2.09
-0.769
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
250
12.76
6
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
0
E
0
Q
2
G
1
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C78H127N33O19S4
1959.32
10.72
+5
2.09
-0.769
Free
L
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, Hgf, C2C12 Cells

Assay & Model

A. favus fungus
A. favus fungus

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
GFP and FITC at N-terminus
GMA4C-GFP penetrated the cells exceptionally well than alone GFP.
Caveolae mediated endocytosis
In vitro and in vivo
CCSCCCCSSTTCSCCCC
Additional Detail Fields 1 fields
CCSCCCCSSTTCSCCCC