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Peptide record

TPDB03927

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB03927
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
LRHKVYGYCVLGP
Physicochemical Analysis
C70H109N19O16S1
ANDEQIMFSTW
GLYV
1504.81
9.59
3
0
6
+2
0.13
0.146
104.62
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
198.03
3
Residue Composition
number
0
A
1
R
0
N
0
D
1
C
0
E
0
Q
2
G
1
H
0
I
2
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 2 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
13
C70H109N19O16S1
1504.81
9.59
+2
0.13
0.146
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 11775 (MIC 64 ug/ml), and C. albicans ATCC 14053 (MIC 64 ug/ml). Note that the mature sequence may differ from
Evidence 2 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

Active against E. coli ATCC 11775 (MIC 64 ug/ml), and C. albicans ATCC 14053 (MIC 64 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 3 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 11775 (MIC 64 ug/ml), and C. albicans ATCC 14053 (MIC 64 ug/ml). Note that the mature sequence may differ from
Evidence 4 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 11775 (MIC 64 ug/ml), and C. albicans ATCC 14053 (MIC 64 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
0% Hemolysis | 80 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Periplanetasin-4, a novel antimicrobial peptide from the cockroach, inhibits communications between mitochondria and vacuoles. | Biochem J | 2019
Evidence 6 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016