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Peptide record

TPDB03924

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB03924
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept AI4AVP dbAMP 3.0 DRAMP APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLPVCGETCFGGTCNTPGCICDPWPVCTRN
Physicochemical Analysis
C129H198N36O41S6
AQHKMSY
C
3101.57
4.07
1
2
6
-1
2.16
0.130
45.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
189.42
12
Residue Composition
number
0
A
1
R
2
N
1
D
6
C
1
E
0
Q
5
G
0
H
1
I
1
L
0
K
0
M
1
F
4
P
0
S
4
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 1 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 1 L: 1 K: 0 M: 0 F: 1 P: 4 S: 0 T: 4 W: 1 Y: 0 V: 2
Chemical Descriptors
30
C129H198N36O41S6
3101.57
4.07
-1
2.16
0.130
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
6.6±1.3 µM
Hemolytic Cytotoxic
50% Hemolysis | 6.6±1.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis. | Biopolymers | 2010
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.