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Peptide record

TPDB03911

Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB03911
Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept MLCPP 2.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VDKGSYLPRPTPPRPIYNRN
Physicochemical Analysis
C105H166N32O29
ACEQHMFW
P
2340.67
10.58
4
1
5
+3
5.34
-1.395
53.50
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
2980
127.31
6
Residue Composition
number
0
A
3
R
2
N
1
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
1
K
0
M
0
F
5
P
1
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 5 S: 1 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
20
C105H166N32O29
2340.67
10.58
+3
5.34
-1.395
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5-10 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or
Evidence 2 Activity

Activity

MIC
Antibacterial
1-2.5 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP

Other

Active against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC
Evidence 3 Activity

Activity

MIC
Antibacterial
1-10 µM

Target

Escherichia coli D22 or 1106

Source & Reference

dbAMP DRAMP

Other

tive against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC 5-10 uM), P. aeruginosa ATCC 82118 (MIC 5-10 uM), other b
Evidence 4 Activity

Activity

MIC
Antibacterial
5-10 µM

Target

Pseudomonas aeruginosa ATCC 82118

Source & Reference

dbAMP DRAMP

Other

(MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC 5-10 uM), P. aeruginosa ATCC 82118 (MIC 5-10 uM), other bacteria > 10 uM. Chemical modification: The Thr is O-glycosylated. Structure: Ric
Evidence 5 Activity

Activity

MIC
Antifungal
5-10 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or
Evidence 6 Activity

Activity

MIC
Antifungal
1-2.5 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC
Evidence 7 Activity

Activity

MIC
Antifungal
1-10 µM

Target

Escherichia coli D22 or 1106

Source & Reference

dbAMP DRAMP Antifungipept

Other

tive against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC 5-10 uM), P. aeruginosa ATCC 82118 (MIC 5-10 uM), other b
Evidence 8 Activity

Activity

MIC
Antifungal
5-10 µM

Target

Pseudomonas aeruginosa ATCC 82118

Source & Reference

dbAMP DRAMP Antifungipept

Other

(MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC 5-10 uM), P. aeruginosa ATCC 82118 (MIC 5-10 uM), other bacteria > 10 uM. Chemical modification: The Thr is O-glycosylated. Structure: Ric
Evidence 9 Activity

Activity

MIC
Antiparasitic
5-10 µM

Target

M. luteus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or
Evidence 10 Activity

Activity

MIC
Antiparasitic
1-2.5 µM

Target

B. megaterium

Source & Reference

DRAMP

Other

Active against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC
Evidence 11 Activity

Activity

MIC
Antiparasitic
1-10 µM

Target

Escherichia coli D22 or 1106

Source & Reference

DRAMP

Other

tive against M. luteus (MIC 5-10 uM), B. megaterium (MIC 1-2.5 uM), S-aureus (MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC 5-10 uM), P. aeruginosa ATCC 82118 (MIC 5-10 uM), other b
Evidence 12 Activity

Activity

MIC
Antiparasitic
5-10 µM

Target

Pseudomonas aeruginosa ATCC 82118

Source & Reference

DRAMP

Other

(MIC>10 uM), E. coli D22 or 1106 (MIC 1-10 uM) or lower, E cloacae beta12 (MIC 5-10 uM), P. aeruginosa ATCC 82118 (MIC 5-10 uM), other bacteria > 10 uM. Chemical modification: The Thr is O-glycosylated. Structure: Ric