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Peptide record

TPDB03910

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB03910
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb AI4AVP dbAMP 3.0 ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVIDAAKKVVNVLKNLF
Physicochemical Analysis
C85H146N22O22
RCEQHMPSTWY
V
1828.23
10.32
3
1
10
+2
2.43
0.747
148.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
2
N
1
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
3
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
17
C85H146N22O22
1828.23
10.32
+2
2.43
0.747
Evidence Records 32 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

S. uberis

Source & Reference

dbAMP DRAMP

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.m
Evidence 3 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. lu
Evidence 4 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

B. cereus

Source & Reference

dbAMP DRAMP

Other

nst L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L
Evidence 5 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

g/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentrati
Evidence 7 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

L. innocua

Source & Reference

dbAMP DRAMP

Other

), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentration that is also toxic to T cell
Evidence 8 Activity

Activity

MIC
Antifungal
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S
Evidence 9 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

S. uberis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.m
Evidence 10 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. lu
Evidence 11 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

B. cereus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

nst L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L
Evidence 12 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml).
Evidence 13 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentrati
Evidence 14 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

L. innocua

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentration that is also toxic to T cell
Evidence 15 Activity

Activity

MIC
Antiparasitic
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S
Evidence 16 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

S. uberis

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.m
Evidence 17 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. lu
Evidence 18 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

B. cereus

Source & Reference

dbAMP 3.0 DRAMP

Other

nst L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L
Evidence 19 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP 3.0 DRAMP

Other

), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml).
Evidence 20 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

M. luteus

Source & Reference

dbAMP 3.0 DRAMP

Other

g/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentrati
Evidence 21 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

L. innocua

Source & Reference

dbAMP 3.0 DRAMP

Other

), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentration that is also toxic to T cell
Evidence 22 Activity

Activity

MIC
Antiviral
3 µg/mL

Target

L. lactis

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S
Evidence 23 Activity

Activity

MIC
Antiviral
12.5 µg/mL

Target

S. uberis

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.m
Evidence 24 Activity

Activity

MIC
Antiviral
12.5 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. lu
Evidence 25 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

B. cereus

Source & Reference

dbAMP 3.0 DRAMP

Other

nst L. lactis (MIC 3 ug/ml), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L
Evidence 26 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP 3.0 DRAMP

Other

), S. uberis (MIC 12.5 ug/ml), S. epidermidis (MIC 12.5 ug/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml).
Evidence 27 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

M. luteus

Source & Reference

dbAMP 3.0 DRAMP

Other

g/ml), B. cereus (MIC 25 ug/ml), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentrati
Evidence 28 Activity

Activity

MIC
Antiviral
50 µg/mL

Target

L. innocua

Source & Reference

dbAMP 3.0 DRAMP

Other

), S. aureus (MIC 25 ug/ml), P.multocida (MIC > 100 ug/ml), M. luteus (MIC 25 ug/ml), and L. innocua (MIC 50 ug/ml). This peptide could inhibit HIV infection at a concentration that is also toxic to T cell
Evidence 29 Activity

Activity

10% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 30 Activity

Activity

50% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 31 Activity

Activity

IC50
Toxicity
17.14±4.32 µg/mL
Cytotoxic
IC50 | 17.14±4.32 | µg/mL | target cell: Human vaginal epithelial cells VK2/E6E7

Target

Human vaginal epithelial cells VK2/E6E7

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 32 Activity

Activity

IC50
Toxicity
17.60±2.52 µg/mL
Cytotoxic
IC50 | 17.60±2.52 | µg/mL | target cell: Human esophagus epithelial cells Het-1A

Target

Human esophagus epithelial cells Het-1A

Source & Reference

NA
DBAASP
Host defence peptides from the skin glands of the Australian blue mountains tree-frog Litoria citropa. Solution structure of the antibacterial peptide citropin 1.1 | Eur J Biochem | 1999