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Peptide record

TPDB03909

Antibacterial Anticancer Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB03909
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GKPICGETCFKGKCYTPGCTCSYPICKKN
Physicochemical Analysis
C134H213N35O39S6
ARDQHLMWV
C
3130.74
8.57
5
1
5
+4
4.26
-0.400
26.90
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
107.16
13
Residue Composition
number
0
A
0
R
1
N
0
D
6
C
1
E
0
Q
4
G
0
H
2
I
0
L
5
K
0
M
1
F
3
P
1
S
3
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 4 H: 0 I: 2 L: 0 K: 5 M: 0 F: 1 P: 3 S: 1 T: 3 W: 0 Y: 2 V: 0
Chemical Descriptors
29
C134H213N35O39S6
3130.74
8.57
+4
4.26
-0.400
Evidence Records 2 records
Evidence 1 Activity

Activity

CC50
Toxicity
5.39±0.33 µM
Cytotoxic
CC50 | 5.39±0.33 | µM | target cell: Human foreskin fibroblasts (HFF)

Target

Human foreskin fibroblasts (HFF)

Source & Reference

NA
DBAASP
Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae. | ACS Chem Biol | 2015
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: HFF-1: CC50=5.39±0.33µM

Target

erythrocytes

Source & Reference

NA
DRAMP
ACS Chem Biol. 2015 Nov 20 10(11):2491-500.