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Peptide record

TPDB03905

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB03905
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILDSFKGVAKGVAKDLAGKLLDKLKCKITGC
Physicochemical Analysis
C147H257N39O41S2
RNEQHMPWY
K
3291.01
9.91
7
3
13
+4
5.54
0.259
112.81
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.80
4
Residue Composition
number
3
A
0
R
0
N
3
D
2
C
0
E
0
Q
5
G
0
H
2
I
5
L
7
K
0
M
1
F
0
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 3 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 2 L: 5 K: 7 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
32
C147H257N39O41S2
3291.01
9.91
+4
5.54
0.259
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
11 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
strongly active against S. aureus (MIC 11 uM), E. coli (MIC 4 uM), and C.albicans (MIC> 150 uM). Also active against B. dendrobatidis (
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

strongly active against S. aureus (MIC 11 uM), E. coli (MIC 4 uM), and C.albicans (MIC> 150 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smi
Evidence 3 Activity

Activity

MIC
Antifungal
11 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
strongly active against S. aureus (MIC 11 uM), E. coli (MIC 4 uM), and C.albicans (MIC> 150 uM). Also active against B. dendrobatidis (
Evidence 4 Activity

Activity

MIC
Antifungal
4 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

strongly active against S. aureus (MIC 11 uM), E. coli (MIC 4 uM), and C.albicans (MIC> 150 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smi
Evidence 5 Activity

Activity

MIC
Antiparasitic
11 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
strongly active against S. aureus (MIC 11 uM), E. coli (MIC 4 uM), and C.albicans (MIC> 150 uM). Also active against B. dendrobatidis (
Evidence 6 Activity

Activity

MIC
Antiparasitic
4 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

strongly active against S. aureus (MIC 11 uM), E. coli (MIC 4 uM), and C.albicans (MIC> 150 uM). Also active against B. dendrobatidis (Table 1, Rollins-Smi
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis. | Dev Comp Immunol | 2011
Evidence 8 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.