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Peptide record

TPDB03904

Antibacterial Hemolysis Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB03904
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GFGTILKALAKIAGKVVKKLATKPGATYMLKENLK
Physicochemical Analysis
C172H298N44O43S1
RDCQHSW
K
3702.59
10.78
8
1
17
+7
4.84
0.151
108.86
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
40.24
5
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
0
H
2
I
5
L
8
K
1
M
1
F
1
P
0
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 0 I: 2 L: 5 K: 8 M: 1 F: 1 P: 1 S: 0 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
35
C172H298N44O43S1
3702.59
10.78
+7
4.84
0.151
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
2.6 µM
Hemolytic Cytotoxic
50% Hemolysis | 2.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
N-terminal aromatic residues closely impact the cytolytic activity of cupiennin 1a, a major spider venom peptide. | Toxicon | 2013
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis