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Peptide record

TPDB03882

Antibacterial Hemolysis Toxicity standard
45 amino acids
Basic Information
3D PDB MODEL
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TPDB03882
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 45-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KKLFKKILKYLAGPAKKLFKKILKYLAGPAKKLFKKILKYLKDEL
Physicochemical Analysis
C263H443N61O53
RNCQHMSTWV
K
5307.79
10.79
16
2
23
+14
6.59
-0.227
121.56
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
4470
84.22
3
Residue Composition
number
4
A
0
R
0
N
1
D
0
C
1
E
0
Q
2
G
0
H
3
I
10
L
16
K
0
M
3
F
2
P
0
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 3 L: 10 K: 16 M: 0 F: 3 P: 2 S: 0 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
45
C263H443N61O53
5307.79
10.79
+14
6.59
-0.227
Evidence Records 4 records
Evidence 1 Activity

Activity

89% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
89% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 2 Activity

Activity

98% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
98% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 3 Activity

Activity

100% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
100% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis