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Peptide record

TPDB03870

Antibacterial Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB03870
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GGGGLRKRLRKFRNKCKEKLKKCGQKIQGLLPKLA
Physicochemical Analysis
C174H313N59O41S2
DHMSTWYV
K
3951.89
11.65
13
1
9
+12
10.81
-0.977
80.86
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.16
5
Residue Composition
number
1
A
4
R
1
N
0
D
2
C
1
E
2
Q
6
G
0
H
1
I
6
L
9
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 0 C: 2 E: 1 Q: 2 G: 6 H: 0 I: 1 L: 6 K: 9 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
35
C174H313N59O41S2
3951.89
11.65
+12
10.81
-0.977
Evidence Records 1 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
<10% Hemolysis | 32 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria. | Chembiochem | 2018