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Peptide record

TPDB03866

Antibacterial Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB03866
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 32-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GGGCGLRRLGCKIAHGVKKYGPTVLRIIRIAG
Physicochemical Analysis
C146H255N49O35S2
NDEQMFSW
G
3321.06
11.42
8
0
12
+7
3.30
0.209
109.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
48.63
4
Residue Composition
number
2
A
4
R
0
N
0
D
2
C
0
E
0
Q
8
G
1
H
4
I
3
L
3
K
0
M
0
F
1
P
0
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 8 H: 1 I: 4 L: 3 K: 3 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
32
C146H255N49O35S2
3321.06
11.42
+7
3.30
0.209
Evidence Records 1 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
>32 µM
Hemolytic Cytotoxic
<10% Hemolysis | >32 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria. | Chembiochem | 2018