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Peptide record

TPDB03862

Antibacterial Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB03862
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 30-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GGGGRFKRFRKKFKKLFKKLSPVIPLLHLG
Physicochemical Analysis
C166H274N48O32
ANDCEQMTWY
K
3454.30
12.73
11
0
11
+10
3.84
-0.370
87.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
5
G
1
H
1
I
5
L
7
K
0
M
4
F
2
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 1 I: 1 L: 5 K: 7 M: 0 F: 4 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
30
C166H274N48O32
3454.30
12.73
+10
3.84
-0.370
Evidence Records 1 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
<10% Hemolysis | 32 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria. | Chembiochem | 2018