Peptide record

TPDB03860

Antibacterial Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB03860
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 30-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GGGGRFKRFRKKCKKLFKKCSPVIPLLHLG
Physicochemical Analysis
C157H264N48O32S2
ANDEQMTWY
K
3400.25
11.66
11
0
9
+10
5.05
-0.423
74.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.68
3
Residue Composition
number
0
A
3
R
0
N
0
D
2
C
0
E
0
Q
5
G
1
H
1
I
4
L
7
K
0
M
3
F
2
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 5 H: 1 I: 1 L: 4 K: 7 M: 0 F: 3 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
30
C157H264N48O32S2
3400.25
11.66
+10
5.05
-0.423
Evidence Records 1 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
>32 µM
Hemolytic Cytotoxic
<10% Hemolysis | >32 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria. | Chembiochem | 2018