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Peptide record

TPDB03821

Antibacterial Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB03821
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
MQFITDLIKKAVDVIKGLFGNK
Physicochemical Analysis
C115H192N28O30S1
RCEHPSWY
K
2479.02
10.16
4
2
11
+2
3.01
0.350
119.55
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
1
N
2
D
0
C
0
E
1
Q
2
G
0
H
3
I
2
L
4
K
1
M
2
F
0
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 3 L: 2 K: 4 M: 1 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C115H192N28O30S1
2479.02
10.16
+2
3.01
0.350
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
8.33 µM
Hemolytic Cytotoxic
10% Hemolysis | 8.33 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of amino acid substitution in the staphylococcal peptides warnericin RK and PSM? on their anti-Legionella and hemolytic activities. | Mol Cell Biochem | 2015
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis