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Peptide record

TPDB03696

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB03696
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
WKWKCTKSGCKWKW
Physicochemical Analysis
C89H127N23O17S2
ARNDEQHILMFPYV
K
1855.25
10.39
5
0
4
+5
-2.65
-1.429
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22125
1192.56
4
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
0
L
5
K
0
M
0
F
0
P
1
S
1
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 1 T: 1 W: 4 Y: 0 V: 0
Chemical Descriptors
14
C89H127N23O17S2
1855.25
10.39
+5
-2.65
-1.429
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designed symmetrical β-hairpin peptides for treating multidrug-resistant salmonella typhimurium infections. | Eur J Med Chem | 2022