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Peptide record

TPDB03665

Antibacterial Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB03665
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
YKLFKKILKKL
Physicochemical Analysis
C72H124N16O13
ARNDCEQGHMPSTWV
K
1421.88
10.77
5
0
6
+5
0.89
-0.191
141.82
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
104.79
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C72H124N16O13
1421.88
10.77
+5
0.89
-0.191
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5-5.0 µM

Target

v. syringae

Source & Reference

NA

Other

active against plant pathogenic bacterial strains P. syringae pv. syringae (MIC 2.5-5.0 uM), X. axonopodis pv. vesicatoria (MIC 2.5-5.0 uM), and E-amylovora (MIC >7.5 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
2.5-5.0 µM

Target

v. vesicatoria

Source & Reference

NA

Other

nt pathogenic bacterial strains P. syringae pv. syringae (MIC 2.5-5.0 uM), X. axonopodis pv. vesicatoria (MIC 2.5-5.0 uM), and E-amylovora (MIC >7.5 uM).
Evidence 3 Activity

Activity

81% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
81% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A library of linear undecapeptides with bactericidal activity against phytopathogenic bacteria. | Peptides | 2007
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis