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Peptide record

TPDB03592

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB03592
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 50-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
Physicochemical Analysis
C254H410N82O74S6
HMV
R
5988.91
9.17
12
6
13
+6
13.57
-1.008
50.80
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
10345
172.74
17
Residue Composition
number
2
A
8
R
2
N
2
D
6
C
4
E
1
Q
3
G
0
H
2
I
4
L
4
K
0
M
1
F
2
P
2
S
3
T
1
W
3
Y
0
V
Amino Acid Distribution
A: 2 R: 8 N: 2 D: 2 C: 6 E: 4 Q: 1 G: 3 H: 0 I: 2 L: 4 K: 4 M: 0 F: 1 P: 2 S: 2 T: 3 W: 1 Y: 3 V: 0
Chemical Descriptors
50
C254H410N82O74S6
5988.91
9.17
+6
13.57
-1.008
Evidence Records 6 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 25922, E. faecalis.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 25922, E. faecalis.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922, E. faecalis.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922, E. faecalis.
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
40 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 40 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Chimeric Cationic Peptide Composed of Human β-Defensin 3 and Human β-Defensin 4 Exhibits Improved Antibacterial Activity and Salt Resistance. | Front Microbiol | 2021
Evidence 6 Activity

Activity

0% Killing
Toxicity
40 µg/mL
Cytotoxic
0% Killing | 40 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
A Chimeric Cationic Peptide Composed of Human β-Defensin 3 and Human β-Defensin 4 Exhibits Improved Antibacterial Activity and Salt Resistance. | Front Microbiol | 2021