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Peptide record

TPDB03590

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB03590
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP AVPpred-BWR
standard
No
A 50-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
RMCKTPSGKFKGYCVNNTNCKNVCRTEGFPTGSCDFHVAGRKCYCYKPCP
Physicochemical Analysis
C238H369N71O68S9
QILW
C
5601.52
8.95
10
2
11
+7
8.61
-0.662
19.40
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
4970
88.73
21
Residue Composition
number
1
A
3
R
4
N
1
D
8
C
1
E
0
Q
5
G
1
H
0
I
0
L
6
K
1
M
3
F
4
P
2
S
4
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 1 R: 3 N: 4 D: 1 C: 8 E: 1 Q: 0 G: 5 H: 1 I: 0 L: 0 K: 6 M: 1 F: 3 P: 4 S: 2 T: 4 W: 0 Y: 3 V: 3
Chemical Descriptors
50
C238H369N71O68S9
5601.52
8.95
+7
8.61
-0.662
Evidence Records 12 records
Evidence 1 Activity

Activity

IC50
Antibacterial
16.2 µM

Target

B. pumilus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
ml), moderate activity against C. albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also
Evidence 2 Activity

Activity

IC50
Antibacterial
10.8 µM

Target

P. carotovorum

Source & Reference

dbAMP DRAMP

Other

albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human s
Evidence 3 Activity

Activity

IC50
Antibacterial
20.4 µM

Target

P. carotovorum

Source & Reference

dbAMP DRAMP

Other

gainst bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human saliva. Updated 12/2014 12/2017 GW.
Evidence 4 Activity

Activity

IC50
Antifungal
16.2 µM

Target

B. pumilus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
ml), moderate activity against C. albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also
Evidence 5 Activity

Activity

IC50
Antifungal
10.8 µM

Target

P. carotovorum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human s
Evidence 6 Activity

Activity

IC50
Antifungal
20.4 µM

Target

P. carotovorum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

gainst bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human saliva. Updated 12/2014 12/2017 GW.
Evidence 7 Activity

Activity

IC50
Antiparasitic
16.2 µM

Target

B. pumilus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
ml), moderate activity against C. albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also
Evidence 8 Activity

Activity

IC50
Antiparasitic
10.8 µM

Target

P. carotovorum

Source & Reference

DRAMP

Other

albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human s
Evidence 9 Activity

Activity

IC50
Antiparasitic
20.4 µM

Target

P. carotovorum

Source & Reference

DRAMP

Other

gainst bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human saliva. Updated 12/2014 12/2017 GW.
Evidence 10 Activity

Activity

IC50
Antiviral
16.2 µM

Target

B. pumilus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
ml), moderate activity against C. albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also
Evidence 11 Activity

Activity

IC50
Antiviral
10.8 µM

Target

P. carotovorum

Source & Reference

DRAMP

Other

albicans and T. reesei. Activity against bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human s
Evidence 12 Activity

Activity

IC50
Antiviral
20.4 µM

Target

P. carotovorum

Source & Reference

DRAMP

Other

gainst bacteria Gram+ B. pumilus (IC50 16.2 uM), Gram- P. carotovorum (IC50 10.8 uM), and P. carotovorum (IC50 20.4 uM). The peptide also inhibits alpha-amylases from human saliva. Updated 12/2014 12/2017 GW.