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Peptide record

TPDB03582

Antibacterial Hemolysis Toxicity standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB03582
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 48-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KKLFKKILKYLTTGLPALISAGPASILAPLGTTLYKLIKKFLKKKDEL
Physicochemical Analysis
C256H435N59O61
RNCQHMWV
LK
5315.63
10.66
11
2
23
+9
4.12
0.202
130.21
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
56.06
8
Residue Composition
number
4
A
0
R
0
N
1
D
0
C
1
E
0
Q
3
G
0
H
4
I
11
L
11
K
0
M
2
F
3
P
2
S
4
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 4 L: 11 K: 11 M: 0 F: 2 P: 3 S: 2 T: 4 W: 0 Y: 2 V: 0
Chemical Descriptors
48
C256H435N59O61
5315.63
10.66
+9
4.12
0.202
Evidence Records 3 records
Evidence 1 Activity

Activity

91% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
91% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
100% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis