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Peptide record

TPDB03536

Cecropin 2 Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB03536
Cecropin 2
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept CAFPdb
standard
No
A 39-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GWLKKIGKKIERVGQHTRDATIQTIGVAQQAANVAATLK
Physicochemical Analysis
C185H316N58O53
CMFPSY
A
4200.90
11.08
8
2
16
+5
9.10
-0.321
97.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
130.92
9
Residue Composition
number
6
A
2
R
1
N
1
D
0
C
1
E
4
Q
4
G
1
H
4
I
2
L
5
K
0
M
0
F
0
P
0
S
4
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 6 R: 2 N: 1 D: 1 C: 0 E: 1 Q: 4 G: 4 H: 1 I: 4 L: 2 K: 5 M: 0 F: 0 P: 0 S: 0 T: 4 W: 1 Y: 0 V: 3
Chemical Descriptors
39
C185H316N58O53
4200.90
11.08
+5
9.10
-0.321
Free
L
Not Available
Free
Antibacterial
The Medfly, Ceratitis capitata also housefly, Musca domestica
Evidence Records 2 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Leukemia Cancer
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1993

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

<5% Hemolysis
Toxicity
1024 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 1024 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria. | J Antimicrob Chemother | 2018