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Peptide record

TPDB03527

Antibacterial Anticancer Antifungal Antiparasitic standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB03527
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
NPVSCVRNKGICVPIRCPGNMKQIGTCVGRAVKCCRKK
Physicochemical Analysis
C170H303N59O45S7
DEHLFWY
C
4118.06
10.39
9
0
10
+9
9.27
-0.163
71.58
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
375
9.11
12
Residue Composition
number
1
A
4
R
3
N
0
D
6
C
0
E
1
Q
4
G
0
H
3
I
0
L
5
K
1
M
0
F
3
P
1
S
1
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 1 R: 4 N: 3 D: 0 C: 6 E: 0 Q: 1 G: 4 H: 0 I: 3 L: 0 K: 5 M: 1 F: 0 P: 3 S: 1 T: 1 W: 0 Y: 0 V: 5
Chemical Descriptors
38
C170H303N59O45S7
4118.06
10.39
+9
9.27
-0.163
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against M. haemolytica, H. somni, P. multocida (Gram+ and viruses are not evaluated).This natural NAP variant is more active than the original form ( AP235 ). Since there is only one residue change, it is predicted to have a beta structure as well. UPdated 6/2016.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against M. haemolytica, H. somni, P. multocida (Gram+ and viruses are not evaluated).This natural NAP variant is more active than the original form ( AP235 ). Since there is only one residue change, it is predicted to have a beta structure as well. UPdated 6/2016.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

Active against M. haemolytica, H. somni, P. multocida (Gram+ and viruses are not evaluated).This natural NAP variant is more active than the original form ( AP235 ). Since there is only one residue change, it is predicted to have a beta structure as well. UPdated 6/2016.