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Peptide record

TPDB03525

Antibacterial Anticancer Antifungal Antiparasitic standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB03525
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGCPFNQGACHRHCRSIRRRGGYCAGLFKQTCTCYR
Physicochemical Analysis
C177H273N63O46S6
DEMWV
RCG
4211.87
9.70
9
0
9
+7
2.35
-0.576
26.49
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
79.66
14
Residue Composition
number
2
A
6
R
1
N
0
D
6
C
0
E
2
Q
6
G
2
H
1
I
1
L
1
K
0
M
3
F
1
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 1 D: 0 C: 6 E: 0 Q: 2 G: 6 H: 2 I: 1 L: 1 K: 1 M: 0 F: 3 P: 1 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
37
C177H273N63O46S6
4211.87
9.70
+7
2.35
-0.576
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.25-1.33 µM

Target

Staphylococcus aureus ATCC6538 or AB94004

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against Gram+ bacteria S. aureus ATCC6538 or AB94004 (MIC 0.25-1.33 uM) and S. epidermidis (MIC 0.5 uM) ( Yang et al., 2024 ). Updated 7/2021 11/2024
Evidence 2 Activity

Activity

MIC
Antibacterial
0.5 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

active against Gram+ bacteria S. aureus ATCC6538 or AB94004 (MIC 0.25-1.33 uM) and S. epidermidis (MIC 0.5 uM) ( Yang et al., 2024 ). Updated 7/2021 11/2024
Evidence 3 Activity

Activity

MIC
Antifungal
0.25-1.33 µM

Target

Staphylococcus aureus ATCC6538 or AB94004

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against Gram+ bacteria S. aureus ATCC6538 or AB94004 (MIC 0.25-1.33 uM) and S. epidermidis (MIC 0.5 uM) ( Yang et al., 2024 ). Updated 7/2021 11/2024
Evidence 4 Activity

Activity

MIC
Antifungal
0.5 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP Antifungipept

Other

active against Gram+ bacteria S. aureus ATCC6538 or AB94004 (MIC 0.25-1.33 uM) and S. epidermidis (MIC 0.5 uM) ( Yang et al., 2024 ). Updated 7/2021 11/2024
Evidence 5 Activity

Activity

MIC
Antiparasitic
0.25-1.33 µM

Target

Staphylococcus aureus ATCC6538 or AB94004

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against Gram+ bacteria S. aureus ATCC6538 or AB94004 (MIC 0.25-1.33 uM) and S. epidermidis (MIC 0.5 uM) ( Yang et al., 2024 ). Updated 7/2021 11/2024
Evidence 6 Activity

Activity

MIC
Antiparasitic
0.5 µM

Target

Staphylococcus epidermidis

Source & Reference

DRAMP

Other

active against Gram+ bacteria S. aureus ATCC6538 or AB94004 (MIC 0.25-1.33 uM) and S. epidermidis (MIC 0.5 uM) ( Yang et al., 2024 ). Updated 7/2021 11/2024