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Peptide record

TPDB03518

Antibacterial Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB03518
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 37-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLRKRLRKFRNKHKEKLKKIGQKIQGLLPKLAPRTDY
Physicochemical Analysis
C202H352N66O47
CMSWV
K
4457.43
11.96
15
2
11
+12
13.60
-1.305
87.03
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
33.43
5
Residue Composition
number
1
A
5
R
1
N
1
D
0
C
1
E
2
Q
3
G
1
H
2
I
6
L
9
K
0
M
1
F
2
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 1 D: 1 C: 0 E: 1 Q: 2 G: 3 H: 1 I: 2 L: 6 K: 9 M: 0 F: 1 P: 2 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
37
C202H352N66O47
4457.43
11.96
+12
13.60
-1.305
Evidence Records 1 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Dissection of the antimicrobial and hemolytic activity of Cap18: Generation of Cap18 derivatives with enhanced specificity. | PLoS One | 2018