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Peptide record

TPDB03491

Antibacterial Hemolysis Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB03491
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RRSQARKCSRGNGGKIGSIRCRGGGTRLGGGSLIGR
Physicochemical Analysis
C146H266N64O44S2
DEHMFPWYV
G
3686.24
12.63
10
0
6
+10
7.53
-0.867
56.94
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
3.39
9
Residue Composition
number
1
A
8
R
1
N
0
D
2
C
0
E
1
Q
11
G
0
H
3
I
2
L
2
K
0
M
0
F
0
P
4
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 8 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 11 H: 0 I: 3 L: 2 K: 2 M: 0 F: 0 P: 0 S: 4 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
36
C146H266N64O44S2
3686.24
12.63
+10
7.53
-0.867
Evidence Records 4 records
Evidence 1 Activity

Activity

8% Hemolysis
Toxicity
1.24 µM
Hemolytic Cytotoxic
8% Hemolysis | 1.24 | µM | target cell: Salmon erythrocytes

Target

Salmon erythrocytes

Source & Reference

NA
DBAASP
Evidence of an antimicrobial-immunomodulatory role of Atlantic salmon cathelicidins during infection with Yersinia ruckeri. | PLoS One | 2011
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
50% Hemolysis | 150 | µM | target cell: Salmon erythrocytes

Target

Salmon erythrocytes

Source & Reference

NA
DBAASP
Evidence of an antimicrobial-immunomodulatory role of Atlantic salmon cathelicidins during infection with Yersinia ruckeri. | PLoS One | 2011
Evidence 3 Activity

Activity

58% Hemolysis
Toxicity
300 µM
Hemolytic Cytotoxic
58% Hemolysis | 300 | µM | target cell: Salmon erythrocytes

Target

Salmon erythrocytes

Source & Reference

NA
DBAASP
Evidence of an antimicrobial-immunomodulatory role of Atlantic salmon cathelicidins during infection with Yersinia ruckeri. | PLoS One | 2011
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis