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Peptide record

TPDB03485

Antibacterial Antifungal standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB03485
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
RPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP
Physicochemical Analysis
C206H302N56O37
ANDCEQHKMSTWV
P
4155.02
12.80
7
0
9
+7
5.76
-1.026
33.43
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
35.86
1
Residue Composition
number
0
A
7
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
0
K
0
M
5
F
18
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 0 F: 5 P: 18 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
35
C206H302N56O37
4155.02
12.80
+7
5.76
-1.026
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

chemically synthesized PR-35 was similar to that of PR-39. Active against Gram- bacteria E. coli ATCC 25922 (MIC 3 ug/ml), S. typhimurium ATCC 14028 (MIC 2 ug/ml), P-aeruginosa ATCC 27853 (MIC>32 ug/ml), S-aureu
Evidence 2 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

S. typhimurium ATCC 14028

Source & Reference

NA

Other

similar to that of PR-39. Active against Gram- bacteria E. coli ATCC 25922 (MIC 3 ug/ml), S. typhimurium ATCC 14028 (MIC 2 ug/ml), P-aeruginosa ATCC 27853 (MIC>32 ug/ml), S-aureus ATCC 25923, and B-cereus ATCC 10876 (MI
Evidence 3 Activity

Activity

MIC
Antifungal
3 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

Antifungipept

Other

chemically synthesized PR-35 was similar to that of PR-39. Active against Gram- bacteria E. coli ATCC 25922 (MIC 3 ug/ml), S. typhimurium ATCC 14028 (MIC 2 ug/ml), P-aeruginosa ATCC 27853 (MIC>32 ug/ml), S-aureu
Evidence 4 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

S. typhimurium ATCC 14028

Source & Reference

Antifungipept

Other

similar to that of PR-39. Active against Gram- bacteria E. coli ATCC 25922 (MIC 3 ug/ml), S. typhimurium ATCC 14028 (MIC 2 ug/ml), P-aeruginosa ATCC 27853 (MIC>32 ug/ml), S-aureus ATCC 25923, and B-cereus ATCC 10876 (MI