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Peptide record

TPDB03476

Antibacterial Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB03476
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 34-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
GFKLKGKAKISCLPNGQWSNFPPKCIRECAMVSS
Physicochemical Analysis
C165H266N46O44S4
DHTY
K
3726.45
10.07
6
1
11
+5
4.03
-0.256
60.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
150.95
10
Residue Composition
number
2
A
1
R
2
N
0
D
3
C
1
E
1
Q
3
G
0
H
2
I
2
L
5
K
1
M
2
F
3
P
4
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 0 C: 3 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 2 K: 5 M: 1 F: 2 P: 3 S: 4 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
34
C165H266N46O44S4
3726.45
10.07
+5
4.03
-0.256
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
High therapeutic index of factor C Sushi peptides: potent antimicrobials against Pseudomonas aeruginosa. | Antimicrob Agents Chemother | 2001