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Peptide record

TPDB03475

Antibacterial Anticancer Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB03475
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKVFKKIEKMGRNIRNGIVKAGPKWKVFKKIEK
Physicochemical Analysis
C194H323N55O41S1
DCQHLSTY
K
4114.10
11.42
13
2
13
+11
10.48
-0.900
74.41
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
267.37
2
Residue Composition
number
1
A
2
R
2
N
0
D
0
C
2
E
0
Q
3
G
0
H
4
I
0
L
11
K
1
M
2
F
1
P
0
S
0
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 2 N: 2 D: 0 C: 0 E: 2 Q: 0 G: 3 H: 0 I: 4 L: 0 K: 11 M: 1 F: 2 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 3
Chemical Descriptors
34
C194H323N55O41S1
4114.10
11.42
+11
10.48
-0.900
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>50 µM
Cytotoxic
50% Cell death | >50 | µM | target cell: Mouse fibroblasts 3T6

Target

Mouse fibroblasts 3T6

Source & Reference

NA
DBAASP
Conformational study of a custom antibacterial peptide cecropin B1: implications of the lytic activity. | Biochim Biophys Acta | 2000
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Conformational study of a custom antibacterial peptide cecropin B1: implications of the lytic activity. | Biochim Biophys Acta | 2000
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Srisailam S, Arunkumar AI, Wang W, Yu C, Chen HM.