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Peptide record

TPDB03474

Antibacterial Hemolysis Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB03474
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
HAEHKVKIKVKQKYGQFPQGTEVTYTCSGNYFLM
Physicochemical Analysis
C180H275N47O50S2
RDW
K
3961.57
9.69
7
2
12
+3
7.72
-0.700
51.47
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
4470
112.83
12
Residue Composition
number
1
A
0
R
1
N
0
D
1
C
2
E
3
Q
3
G
2
H
1
I
1
L
5
K
1
M
2
F
1
P
1
S
3
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 1 E: 2 Q: 3 G: 3 H: 2 I: 1 L: 1 K: 5 M: 1 F: 2 P: 1 S: 1 T: 3 W: 0 Y: 3 V: 3
Chemical Descriptors
34
C180H275N47O50S2
3961.57
9.69
+3
7.72
-0.700
Evidence Records 2 records
Evidence 1 Activity

Activity

37% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
37% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
High therapeutic index of factor C Sushi peptides: potent antimicrobials against Pseudomonas aeruginosa. | Antimicrob Agents Chemother | 2001
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis