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Peptide record

TPDB03470

Antibacterial Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB03470
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 33-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
NPEKALEPLIAIQIAIKGMLNGWFTGVGFRRKR
Physicochemical Analysis
C171H279N49O42S1
DCHSY
GI
3725.46
11.46
6
2
15
+4
4.24
-0.079
100.61
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
5500
147.63
4
Residue Composition
number
3
A
3
R
2
N
0
D
0
C
2
E
1
Q
4
G
0
H
4
I
3
L
3
K
1
M
2
F
2
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 3 N: 2 D: 0 C: 0 E: 2 Q: 1 G: 4 H: 0 I: 4 L: 3 K: 3 M: 1 F: 2 P: 2 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
33
C171H279N49O42S1
3725.46
11.46
+4
4.24
-0.079
Evidence Records 1 records
Evidence 1 Activity

Activity

63.2% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
63.2% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Highly potent antimicrobial modified peptides derived from the Acinetobacter baumannii phage endolysin LysAB2. | Sci Rep | 2017