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Peptide record

TPDB03465

Antibacterial Anticancer Antifungal Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB03465
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRIRFRPPYLPRPGRRPRFPPPFPIPRIPRIP
Physicochemical Analysis
C188H300N62O34
ANDCEQHKMSTWV
P
3972.85
13.00
10
0
9
+10
7.38
-1.116
60.94
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
37.50
1
Residue Composition
number
0
A
10
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
4
I
1
L
0
K
0
M
3
F
12
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 4 L: 1 K: 0 M: 0 F: 3 P: 12 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
32
C188H300N62O34
3972.85
13.00
+10
7.38
-1.116
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Tur1A inhibits E. coli.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Tur1A inhibits E. coli.
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
0% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens. | Int J Mol Sci | 2020
Evidence 4 Activity

Activity

20% Killing
Toxicity
32 µM
Cytotoxic
20% Killing | 32 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens. | Int J Mol Sci | 2020