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Peptide record

TPDB03454

T11N2 Antibacterial Anticancer Cell-penetrating Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB03454
T11N2
Antibacterial Anticancer Cell-penetrating Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
Chemical: Marine AMP-N2
Sequence
YGRKKRRQRRRAFCWNVCVYRNAVRVCHRRCN
Physicochemical Analysis
C173H285N71O39S4
DEILMPST
R
4111.86
12.05
13
0
10
+12
7.01
-1.272
42.50
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
8730
212.31
10
Residue Composition
number
2
A
10
R
3
N
0
D
4
C
0
E
1
Q
1
G
1
H
0
I
0
L
2
K
0
M
1
F
0
P
0
S
0
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 10 N: 3 D: 0 C: 4 E: 0 Q: 1 G: 1 H: 1 I: 0 L: 0 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 4
Chemical Descriptors
32
C173H285N71O39S4
4111.86
12.05
+12
7.01
-1.272
Free
Marine AMP-N2
L
Cationic and amphipathic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

RAW264.7, S. Typhimurium

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic and amphipathic
Chimeric
FITC dye
Cytoplasm
T11N2 exhibited a higher internalization ratio than B6N2
Endocytosis and Macropinocytosis
In vitro