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Peptide record

TPDB03444

Antibacterial Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB03444
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 31-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RFRPPIRRPPIRPPFYPPFRPPIRPPIFPPI
Physicochemical Analysis
C187H284N52O33
ANDCEQGHLKMSTWV
P
3788.64
12.80
7
0
10
+7
4.96
-0.694
62.90
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
39.33
1
Residue Composition
number
0
A
7
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
5
I
0
L
0
K
0
M
4
F
14
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 5 L: 0 K: 0 M: 0 F: 4 P: 14 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
31
C187H284N52O33
3788.64
12.80
+7
4.96
-0.694
Evidence Records 1 records
Evidence 1 Activity

Activity

40% Killing
Toxicity
32 µM
Cytotoxic
40% Killing | 32 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Fragments of the Nonlytic Proline-Rich Antimicrobial Peptide Bac5 Kill Escherichia coli Cells by Inhibiting Protein Synthesis. | Antimicrob Agents Chemother | 2018