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Peptide record

TPDB03427

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB03427
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SIGSAFKKALPVAKKIGKAALPIAKAALP
Physicochemical Analysis
C135H235N35O32
RNDCEQHMTWY
A
2860.57
11.21
6
0
16
+6
2.54
0.541
118.28
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
8
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
3
L
6
K
0
M
1
F
3
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 8 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 3 K: 6 M: 0 F: 1 P: 3 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
29
C135H235N35O32
2860.57
11.21
+6
2.54
0.541
Evidence Records 6 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Ctx B was active against Gram-negative E. coli. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Ctx B was active against Gram-negative E. coli. Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Ctx B was active against Gram-negative E. coli. Updated 7/2021
Evidence 4 Activity

Activity

Hemolysis
[Swiss_Prot Entry P36191]has hemolytic activity

Source & Reference

APD_complete APD_hemolytic
DRAMP4
Insect Biochem Mol Biol. 1993 Jul 23(5):591-598.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 5 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Swiss_Prot Entry P36191]has hemolytic activity

Target

erythrocytes

Source & Reference

NA
DRAMP
Insect Biochem Mol Biol. 1993 Jul 23(5):591-598.
Evidence 6 Hemolysis

Activity

[Swiss_Prot Entry P36191]has hemolytic activity
Hemolysis

Source & Reference

APD_complete APD_hemolytic
Insect Biochem Mol Biol. 1993 Jul 23(5):591-598.
DRAMP4
APD_complete APD_hemolytic