Peptide record

TPDB03412

Antibacterial Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB03412
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 28-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKLFKKILKYLAVAVVGQATQIAKKDEL
Physicochemical Analysis
C148H255N37O37
RNCHMPSW
K
3144.88
10.48
7
2
15
+5
6.09
0.111
128.93
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
47.38
4
Residue Composition
number
4
A
0
R
0
N
1
D
0
C
1
E
2
Q
1
G
0
H
2
I
4
L
7
K
0
M
1
F
0
P
0
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 2 L: 4 K: 7 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
28
C148H255N37O37
3144.88
10.48
+5
6.09
0.111
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
10% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 2 Activity

Activity

24% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
24% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 3 Activity

Activity

42% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
42% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013