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Peptide record

TPDB03404

Antibacterial Hemolysis Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB03404
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KKLFKKILKYLGIGAVLKVLTTGLKDEL
Physicochemical Analysis
C150H261N35O36
RNCQHMPSW
LK
3130.94
10.48
7
2
14
+5
3.85
0.371
149.64
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
47.59
3
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
1
E
0
Q
3
G
0
H
2
I
7
L
7
K
0
M
1
F
0
P
0
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 2 L: 7 K: 7 M: 0 F: 1 P: 0 S: 0 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
28
C150H261N35O36
3130.94
10.48
+5
3.85
0.371
Evidence Records 4 records
Evidence 1 Activity

Activity

41% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
41% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 2 Activity

Activity

60% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
60% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 3 Activity

Activity

86% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
86% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis