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Peptide record

TPDB03401

Antibacterial Antiparasitic Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB03401
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GKVLDKFGKIVGKVLKQLKKVSAVAKV
Physicochemical Analysis
C135H242N36O32
RNCEHMPTWY
K
2881.63
10.99
8
1
13
+7
6.85
0.270
129.63
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
0
E
1
Q
3
G
0
H
1
I
3
L
8
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 3 K: 8 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 6
Chemical Descriptors
27
C135H242N36O32
2881.63
10.99
+7
6.85
0.270
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
338 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 338 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Lytic activity and structural differences of amphipathic peptides derived from trialysin. | Biochemistry | 2006
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis