Back to search

Peptide record

TPDB03389

B6N2 Antibacterial Anticancer Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB03389
B6N2
Antibacterial Anticancer Cell-penetrating Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
Chemical: Marine AMP-N2
Sequence
RRWQWRAFCWNVCVYRNAVRVCHRRCN
Physicochemical Analysis
C154H233N57O33S4
DEGILKMPST
R
3539.15
11.64
8
0
11
+7
-0.17
-0.722
50.37
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
18240
515.38
9
Residue Composition
number
2
A
7
R
3
N
0
D
4
C
0
E
1
Q
0
G
1
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
3
W
1
Y
4
V
Amino Acid Distribution
A: 2 R: 7 N: 3 D: 0 C: 4 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 1 V: 4
Chemical Descriptors
27
C154H233N57O33S4
3539.15
11.64
+7
-0.17
-0.722
Free
Marine AMP-N2
L
Cationic and amphipathic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

RAW264.7, S. Typhimurium

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic and amphipathic
Chimeric
FITC dye
Cytoplasm
T11N2 exhibited a higher internalization ratio than B6N2
Macropinocytosis and clathrin mediated endocytosis
In vitro