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Peptide record

TPDB03371

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB03371
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKEFLKEFKEAKKEVLHEALKAISE
Physicochemical Analysis
C148H236N36O40
RNDCQGMPTY
K
3159.72
9.48
8
6
11
+1
13.60
-0.850
82.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
174.07
1
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
6
E
0
Q
0
G
1
H
1
I
3
L
7
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 6 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 7 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C148H236N36O40
3159.72
9.48
+1
13.60
-0.850
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
>1000.0 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | >1000.0 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. | Biopolymers | 2008